Guidelines for Taking CBD


Guidelines for Taking CBD

This article will discuss the following key terms and topics – Bioavailability, Dosages and Dosing, Biphasic Properties, Extraction Methods, Third Party Testing, Natural CBD versus Synthetic CBD.

CBD can be consumed in many ways including ingestion, inhalation, sublingual, absorption, topical absorption, and transdermal absorption. This flexibility has resulted in a wide variety of CBD products including sprays, capsules, soft gels, tinctures, edibles (such as gummies and chewing gum), oil concentrates, lozenges, beverages, vape oil (inhaled via a vaporizer), balm or salve (topical creams), and more. CBD products are also available for pets.

The efficacy of CBD varies among people. Each delivery method and treatment regimen should match a person’s individual needs. There are a number of factors to consider when evaluating what CBD product and dosage works best. They include the ingredients, the potency, and the quality of the product.

Another consideration is bioavailability. This is a measure of the absorption rate, which is the amount of CBD you’ve taken that ends up being used in your body. CBD metabolizes in varying degrees before it gets into the bloodstream. Each method of delivery results in the body taking in the CBD differently. For example, the bioavailability of inhaled CBD is between 20 and 50 percent. The range for CBD tinctures is 10 to 40 percent.

Other variables that influence bioavailability includes your biochemistry and metabolism, what you ate that day, your overall health, and how frequently you consume CBD or other cannabinoids. One way to enhance the bioavailability of CBD is to eat food items that have healthy levels of saturated fats like eggs, avocado, greens, seeds, beef, and lamb.

The bioavailability of CBD is also influenced by water-soluble nanoemulsion technology. This is a process for encapsulating the active compounds in nano-sized (tiny) emulsions. The size of nanoemulsion CBD oil droplets is between 4 and 200 times smaller than the industry standard. The smaller size increases the rate of absorption of CBD into the blood.

Many CBD users prefer non-inhalable products with oil concentrates even though inhalation offers a higher rate of bioavailability and the quickest onset in terms of the effect. By contrast, ingestion of CBD is a slower onset although the effect lasts longer than inhalation. The average onset for all delivery methods is 15 to 30 minutes. The average duration of the effect is 2-4 hours although it can be 6-8 hours if the CBD is ingested. These are guidelines and the actual process varies between individuals.

Adults are encouraged to start with a low dose and that includes the option of taking a few small doses over the course of the day rather than a single big dose.

Adults are encouraged to start with a low dose and that includes the option of taking a few small doses over the course of the day rather than a single big dose. It’s important to use the same dose for several days and to adjust the amount based on self-observation of the effect.

An effective dosage can range from as little as a few milligrams of CBD oil to a gram or more. CBD has biphasic properties, which means that low and high doses of the same substance can produce opposite effects. Small doses tend to stimulate, and large doses tend to sedate. CBD has no known adverse side effects, but an excessive amount of CBD could be less effective therapeutically than a moderate dose.

The quality of the CBD product depends on the source (the hemp plant), how it’s made, the extraction method used to produce the hemp extract, and the remaining ingredients following the extraction process. The best products are not contaminated with toxic substances like heavy metals, herbicides, pesticides, solvents, etc. High quality CBD products also don’t include corn syrup, trans fats, GMOs, artificial additives, thinning agents, or preservatives.

The best way to determine the quality of CBD from hemp extract is through third party lab testing. Testing can verify consistency and the absence of bacteria, pesticides, mold, solvent residues, and other contaminants. Strict quality control is the key for companies maintaining consistency in the content of their CBD products.

Understanding CBD product labels can be challenging because there are no current uniform standards on what the labels should include. The worst consequence for consumers is exposure to unknown chemicals or toxins. Some manufacturers are providing products with lower potency than what’s noted on the label, so avoid products that can’t provide verified third-party lab test results.

Most labels show the quantity of CBD per dose, the serving size, ingredients, and basic instructions for using the product. Some CBD product companies include a QR code that can be scanned to learn about the specific ingredients and third-party test results.

Many single-serving products like edibles will have dosage information by piece or serving size. Other products like tinctures can be more confusing. Most tincture bottles are one ounce although larger bottles are available. There are 30 milliliters in one ounce. The standard dropper size in a tincture bottle is 1 milliliter containing about 20 drops. That equals 30 full droppers per bottle.

It’s also important to know the amount of CBD that’s included in the product. It’s usually noted on the label as the total milligrams or as a percentage. Most CBD products have a range of 350 to 1,000 milligrams of CBD.

Pharmaceutical companies are beginning to produce synthetic CBD in a lab. Big Pharma assert that synthetic options offer better quality control and greater consistency.  One of the possible outcomes from Big Pharma’s investment in developing new synthetic CBD products is a significant increase in the cost for consumers. Big Pharma will likely claim the higher costs are justified to cover their investment in research and quality control standards.

CBD is a safe and non-toxic substance, but it can interact with some pharmaceuticals. At sufficient dosages, CBD may inhibit cytochrome P450 enzymes, thereby altering how we metabolize painkillers, statins, blood thinners, insulin and more. CBD-drug interactions can be dangerous, but they can also help mitigate side effects. For example, cannabinoidopioid interactions show therapeutic potential. THC enhances the painkilling effects of opiates, while CBD can reduce withdrawal and dependence. Patients taking pharmaceutical medications should monitor changes in blood levels. Problematic interactions are more likely when consuming high doses of CBD isolate products. Please consult your physician if you have any questions about drug interactions.

The primary methods of extraction are by alcohol or CO2. The alcohol extraction method is widely used, but many helpful phytochemicals are destroyed in the process. In the CO2 extraction process, all plant substances are preserved. The challenge is that the CO2 method is more expensive since it requires specialized equipment



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